Exposure to Toxins Can Turn Genes On and Off

Exposure to Toxins Can Turn Genes On and Off

Q: I thought I was born with my genes (some from Mom, some from Dad), and they made me who I am. Now I hear that how you live day-to-day turns genes on and off. Does that change who I am, basically? – Mitch D., Mystic, Ct.

Drs. Oz & Roizen
Dr. Michael Roizen & Dr. Mehmet Oz

A: You were born with a set of genes. The DNA-containing chromosomes in those genes determine your gender, your eye color, even your sensitivity to sound. But not all genes are active all the time. And about 80 percent of your genetic material is made up not of genes but of gene switches (which we are just beginning to understand).

These switches cause changes in the way a gene works; this is called gene expression – a smile or a grimace, if you want to think of it that way. Switches can be prodded by things like toxins, stress, behavior and diet into expressing themselves as they were intended to – or not – without altering your DNA. So you stay the same person, but one who, unfortunately, develops cancer, muscular dystrophy or mental illness, for example.

So, how can you help your genes do their job of keeping your healthy, happy and strong?

Exposure to Toxins Can Turn Genes On and OffLimit Exposure to Toxins. Have your house tested for radon (radon occurs naturally in the ground and is the second-leading cause of lung cancer in North America). Eliminate plastics containing bisphenol-A (BPA) and phthalates from your home. Use paints with a low- or no-VOC (volatile organic compounds) rating. Wash fruits and vegetables in water to remove pesticide residue and bacteria. And stay away from smoke (cigarettes, charcoal grills and fireplaces).

Chill It. Chronic stress can flip the switch on genes, making you more susceptible to cancer, heart disease and depression. Meditation for 10 minutes a day lowers levels of the stress hormone cortisol.

Break a Sweat. Exercising 30 minutes a day provides protection against diabetes, heart problems and dementia.

Eat Smart. Eliminate the five food felons (trans fats and most saturated fats, added sugar and sugar syrups, and any grain that isn’t 100 percent whole), and if you are overweight, drop 10 percent of your body weight. It’s a sure gene pleaser, and you’ll make your other jeans happy too!

– Dr. Michael Roizen & Dr. Mehmet Oz

© 2012 Michael Roizen, M.D. and Mehmet Oz, M.D. Distributed by King Features Syndicate, Inc.

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